How to Use Durex Lubricant in 10 Surprising Ways Durex India A penis putting on a condom and applying lubricant and removing after use wrapped in a tissue; a guide to basic condom sense by AIDS: A Positive Co ordinated Community Response Society of This is how to properly use a lubricant with a condm Water based lubricants are safe to use & they help reduce friction during sx, making it more comfortable while keeping the cndom Should you use a lubricant with a condom First off, if youre using lube with a condom, make sure its ALWAYS water or silicone based. Oil based lube can damage your condoms! Now, heres why you should go for lube each and every time:, NO! Only use water based lubes designed for sex. Oil based ones (such as Vaseline, massage oils or hand cream) may weaken or break the condom.