Since their introduction in Europe in 2006 and the U.S. in 2007, the use of e cigarettes a.k.a., vapes has skyrocketed. A recent review from researchers in Australia found the results E Cigarettes (Vapes) Smoking and Tobacco Use CDC Cristina Davis' lab to lead one of the largest studies of vaping to date Mechanical and Aerospace Engineering UC Davis Engineering E Cigarettes and Vape Pens Tobacco Prevention Toolkit Stanford Medicine E cigarette research, USA Stock Image Science Source Images A analysis of more than 100 studies found the vaping can have long term health consequences.