What Happens When You Vape? Vaping and COPD: Is it okay or can it cause more problems? Vaping ups risk of self reported COPD Futurity Smoking and vaping are often compared, but neither is harmless. While they work differently, both can expose the lungs to addictive nicotine and harmful chemicals that impact breathing and overall health. Smoking E cigs: What You Need to Know if You Care for Patients with COPD Challenges in COPD Vaping and COPD